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The transgenic construct comprises the following elements: CAG promoter, a loxP site flanked STOP cassette, the mouse gene, an IRES site, the beta-galactosidase (lacZ) reporter gene, and poly(A) features. The inserted mouse gene and the reporter gene will only be expressed after removal of the STOP cassette through cre-mediated recombination. The pound # sign is used in the symbol where no line is specified. (J:243119)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
