A construct comprising the following elements was inserted into the host locus: CAG promoter, loxP site flanked STOP cassette, transcription start site, sequence for FLAG and Myc epitope tags, cDNA for the A isoform of the mouse progesterone receptor gene Pgr, and poly(A) features. This creates a conditional-ready allele where the inserted gene is only expressed after removal of the STOP cassette through cre-mediated recombination. (J:243133)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S7/SvEvBrd-Hprt1b-m2
Targeted
Insertion
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--
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3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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