A targeting construct was designed to insert a creERT2 fusion gene (a Cre recombinase fused to a human estrogen receptor ligand binding domain) followed by a frt-flanked neomycin resistance (neo) cassette, just downstream of the start codon of the MAS-related GPR, member D (Mrgprd) gene. Breeding to B6.129S4-Gt(ROSA)26Sor/J (Stock No. 007844) removed the neo cassette. (J:245897)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count