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A green fluorescent protein (GFP)-cre recombinase fusion protein, preceded by an internal ribosome entry site (IRES), was inserted into the second exon of the murine gene in BAC clone RP24-276O23, replacing most of the 3' UTR. The engineered BAC DNA was microinjected into fertilized C57BL/6 oocytes. Four independent founder lines were generated, of which one was used for further study. The pound # sign is used in the allele symbol because the line used was not specified. (J:243173)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
