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A genomic clone, containing a 5.5 kb upstream region and the first six exons of the mouse GAD2 (GAD65) gene, was modified to express the eGFP marker gene without its own translation start site. The EGFP cDNA was fused in frame to the third exon of the Gad2 (GAD65) gene. Expression of eGFP occurs almost exclusively in the GABAergic neurons in many brain regions, including the neocortex and hippocampus. Line 30 was created. (J:245841)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
