A loxP site and FRT-flanked puro resistance cassette were inserted in intron 1 and a loxP site was inserted in intron 3 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:229821)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count