The Venus YFP reporter gene was cloned into rat BAC CH230-36N4 or mouse BAC RP23-343C17, replacing the coding region of the rat or mouse glucagon gene (Gcg) from the start codon in exon 2 to the stop codon in exon 6. The final construct was injected into the pronuclei of fertilized (C57BL/6 x CBA)F1 eggs. The estimated copy number of this transgene ranges from 1 to 12. The pound sign (#) is used where the transgenic line used is not specified. (J:238690)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count