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The Venus YFP reporter gene was cloned into mouse BAC RP23-343C17, replacing the coding region of the glucagon gene (Gcg) from the start codon in exon 2 to the stop codon in exon 6. The experimental procedures introduced a nucleotide substitution in the non-coding sequence of exon 2, where it was deemed not to interfere with the expression. The final construct was injected into the pronuclei of fertilized (C57BL/6 x CBA)F1 eggs. The estimated copy number of this transgene is 12. (J:238690)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
