Exon 2 was disrupted with the insertion of an IRES-lacZ-neo cassette. Western blot analysis confirmed the absence of PKN1 expression in homozygous mutant embryo extracts with no compensatory changes in PKN2 or PKN3 expression. (J:229595)
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Exon 2 was disrupted with the insertion of an IRES-lacZ-neo cassette. Western blot analysis confirmed the absence of PKN1 expression in homozygous mutant embryo extracts with no compensatory changes in PKN2 or PKN3 expression. (J:229595)