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A DNA fragment encoding the cre/ERT2 fusion protein with a poly A sequence was inserted at the endogenous ATG translational start site of a murine Pax8 sequence. The construct was injected into C57BL/6J blastocysts. Five transgenic founders were identified, and data for one of them (Line C) is reported. The transgene integration in this line was localized via fluorescence in situ hybridization and paired-end whole genome sequencing to an intergenic region of Chr 6qC1 (chr6:62,912,590-62,912,610; GRCh38/mm10). (J:243751)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
