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A construct (composed of cre recombinase with a nuclear localization signal, SV40 polyadenylation sequence, and an Frt-Kanamycin/neo-Frt cassette) was introduced into the ATG site in exon 2 of the Gpr101 gene in a bacterial artificial chromosome (BAC RP23-203E19) by recombineering in bacterial cells. Modified BAC DNA was purified and injected into mouse pronuclei to produce transgenic mice. Two lines A and B are generated and analized separately. (J:242614)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
