An FRT flanked pgk-neo cassette was inserted in intron 6 and an A to T mutation was inserted in exon 7 creating a Y319F mutation via homologous recombination. Flp mediated recombination removed the neo cassette. The mutation prevents phosphorylation at this site. (J:229022)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6.Cg-Thy1a
Targeted
Insertion, Single point
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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