An FRT flanked pgk-neo cassette was inserted in intron 6 and an A to T mutation was inserted in exon 7 creating a Y319F mutation via homologous recombination. Flp mediated recombination removed the neo cassette. The mutation prevents phosphorylation at this site. (J:229022)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count