A targeting vector containing a FRT site flanked neo cassette with a downstream loxP site was inserted upstream of exon 5. A second loxP site was inserted upstream of exon 4. Flp-mediated recombination removed the neo cassette leaving exon 4 floxed. (J:175858, J:228945)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count