A loxP site was inserted in intron 11 and a loxP site and FRT flanked neo cassette were inserted in intron 12 via homologous recombination. Flp-mediated recombination removed the neo cassette leaving exon 11 floxed. (J:228945)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count