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The transgene was designed with a human bacterial artificial chromosome (BAC) RP11-150L1 containing the entire human TLR4 gene. Founder line 5271 was established and carries two copies of the transgene. The BAC contains at least 50 Kb of human genomic sequences flanking the TLR4 gene. (J:194866)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
