The transgene construct comprises sequence containing the mouse Gata1 hematopoietic regulatory domain (G1-HRD) (3.9 kb sequence 5' of the IE exon, the IE exon, intron 1 and part of exon 2; the initiation ATG codon in exon 2 was replaced with a NotI restriction site) upstream of the mouse Runx1 gene. This allele drives the transgene only in hematopoietic tissue. (J:117242)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x DBA/2)F1
--
Insertion
--
1
--
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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