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A construct consisting of the human beta actin promoter followed by the cDNA for Wlds that is an in-frame fusion of exon 1 and 2 of Ube4b to exon 2 onwards of Nmnat1, was injected into the pronuclei of fertilized (C57BL/6 x CBA)F1 eggs that do not express Wlds. Expression level of this transgene is similar to that of Wlds in the C57Bl/6Ola strain. (J:72936)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
