LoxP sites were inserted surrounding exon 3, which encodes the catalyic domain of the encoded protein. An frt-flanked neomycin selection cassette 3' to exon 3 was removed via FLP-mediated recombination in the final allele. (J:229399)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count