A loxP site and an frt-flnaked neomycin selection cassette was inserted upstream of exon 8, and a single loxP site was inserted downstream of exon 8. FLP-mediated recombination resulted in the removal of the selection cassette in the final allele. (J:229011)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count