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A loxP site was inserted upstream of the gene and an FRT site flanked neomycin resistance gene cassette and a second loxP site were inserted downstream. The neo cassette was removed through subsequent flp-mediated recombination, leaving a conditional-ready allele with the gene floxed. Knockout of the gene through cre-mediated recombination does not affect the Mib1 host gene in which intron it is located. (J:242463)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
