A loxP site was inserted upstream of exon 5 and a loxP site and FRT flanked neo cassette were inserted downstream of exon 5. Flp-mediated recombination removed the neo cassette leaving exon 5 floxed. (J:228281)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count