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The transgene contains pre-arranged Tcr loci from a CD4+ cell line LLO118 (Valpha2 Vbeta2), which recognizes the immunodominant Listeria monocytogenes epitope listeriolysin residues 190-205. Cell line LL056 differs from LLO118 by 15 amino acids in the complementaruty determing regions (CDR). The leader region (from 2B4 TCR) and constant region (C1) were added to the transgene. The pound symbol is used when no line is specified and/or lines are pooled. (J:185522)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
