The transgene contains rearranged MS2-3C8 TCR Valpha (AV4S1AJ32) and Vbeta (BV2S1BJ1S6) chains from the T cell clone MS2-3C8 isolated from the peripheral blood of a patient with relapsing/remitting multiple sclerosis, which recognizes the human MBP 111-129 epitope. Lines B6 and G2 were generated. The pound symbol is used when no line is specified and/or lines are pooled. (J:91285)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
--
Insertion
--
--
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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