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The following elements were inserted in intron 1 of the host locus: a loxP site flanked STOP cassette, the Ripk3 coding sequence with a FLAG tag fused to the 5' end and two FKBPF36V tags to the 3' end, sequence coding for the Thosea asigna virus 2A (T2A) self-cleaving peptide sequence, and the mCherry red fluorescent marker gene. This creates a conditional-ready allele that, after the removal of the stop cassette through cre-mediated recombination, would express the FLAG- and FKBP-tagged Ripk3 peptide and the mCherry reporter. (J:241350)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
