A construct containing a slice acceptor site, floxed-neo-stop cassette, HA-tagged human CARD11 cDNA with an isoleucine codon after the leucine codon at position 225 (L225LI), IRES-eGFP cassette and polyA sequence was inserted in intron 1. The human cDNA was derived from a diffuse large B-cell lymphoma and carries a constitutively active mutation. (J:228288)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count