A construct containing a slice acceptor site, floxed-neo-stop cassette, HA-tagged human CARD11 cDNA with an isoleucine codon after the leucine codon at position 225 (L225LI), IRES-eGFP cassette and polyA sequence was inserted in intron 1. The human cDNA was derived from a diffuse large B-cell lymphoma and carries a constitutively active mutation. (J:228288)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129P2/OlaHsd
Targeted
Insertion
--
--
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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