Log In|Sign Up
EN
A tyrosine to alanine mutation and a phenylalanine to alanine mutation were inserted at position 599 and 600 (Y599A and F600A; TATTTT to GCTGCA) in exon 7 and an FRT flanked neo cassette was inserted at position chr10:18724150 (NCBI37/mm9) via homologous recombination. Flp mediated recombination removed the neo cassette. The mutations compromise ZnF4 ubiquitin binding. (J:228302)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
