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EN
The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 11345bp between positions 136626234-136637578 of Chromosome 5 (Genome Build37), deleting virtually the entire coding region (located on exons 2 and 3). The cassette contains a lacZ reporter gene cassette and a loxP site flanked neomycin resistance gene cassette. The neo gene was removed through subsequent cre-mediated recombination. The absence of transcription and translation from this allele was confirmed by qRT-PCR and immunoblots. (J:241365)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
