An approximately 1.2 Mb deletion spanning from Chrna7 to Fan1 and including the coding regions of both of these genes plus Mtmr10, Trpm1, Klf13 and Otud7a was created by Flp mediated recombination between Chrna7tm1Mima and Fan1tm1Mima. Expression of genes within the region is reduced in brain tissue from heterozygous mice. (J:227984)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6NTac
Targeted
Insertion, Intergenic deletion, Intragenic deletion
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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