The human diphtheria toxin receptor, pro-HB-EGF (precursor of heparin-binding EGF-like growth factor), is under the control of the cardiac-specific alpha-myosin heavy chain promoter. Administration of diphtheria toxin induces ablation of transgene-expressing cardiomyocytes. Two lines were generated, however the pound symbol (#) is used when line is not specified and/or lines are pooled. (J:93335)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x DBA/2)F1
--
Insertion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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