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The transgenic construct contains mouse cDNA containing Cxcr3 inserted into the second exon of and therefore under the control of the hCD2 minigene, which consists of human CD2 gene promoter and exon 1 with a mutant ATG start codon, first intron, 3' UTR polyA signal, and flanking sequence. Flow cytometric analyis in thymus, lymph nodes, and spleen confirms that protein is expressed constitutively in almost all T cells. (J:242971)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
