This allele from project Ccdc85b-8691J-5050M was generated at The Jackson Laboratory by injecting Cas9 RNA and 2 guide sequences CCCTCAGTCATCAGGGGAGC and GGAGGCCGAAGCAGGCGGCC, which resulted in a 680 bp deletion beginning at Chromosome 19 negative strand position 5,457,391 bp, GCCGAAGCAGGCGGCCTGGA, and ending after GCTGTGGACCTCCAGACCTG at 5,456,712 bp (GRCm38/mm10). This mutation deletes all of exon ENSMUSE00001034635 except the first 6 bp and an additional 77 bp of flanking intronic sequence and is predicted to cause early truncation after 2 amino acids. (J:188991)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NJ
Endonuclease-mediated
Intragenic deletion
Not Specified
1
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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