Log In|Sign Up
EN
The following elements were inserted into the locus: a loxP site flanked STOP cassette (consisting of a neomycin resistance gene cassette followed by three SV40 poly(A) sites), the CMV-IE enhancer/chicken beta-actin/rabbit beta-globin (CAG) hybrid promoter, and the rat gene with a p.Met593Ser mutation. This creates a conditional-ready allele from which the rat gene will only be expressed after cre-mediated recombination to remove the STOP cassette. (J:241405)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
