A KOMP (Aclytm184180a(L1L2_Bact_P)) targeting vector containing a FRT-lacZ-loxP-neo-FRT-loxP cassette was introduced to intron 8, and a loxP site was placed in intron 9 via homologous recombination. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exons 9 floxed. (J:240494)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count