The cardiac-specific 5.5-kb murine alpha-MHC promoter drives the expression of a rat cardiac troponin I cDNA truncated at lysine 193 which is missing the 17 COOH-terminal residues. Three lines were generated which have 9 to 13 copies of the transgene. Founder line 1 is the representative line. (J:59433)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count