Log In|Sign Up
EN
The cardiac specific mouse alpha-MHC promoter drives the expression of a mouse mutant alpha-tropomyosin striated muscle specific cDNA with a single nucleotide change, GAA>AAA, corresponding to an amino acid substitution of a glutamic acid to lysine at codon 54 (Glu54Lys). Five lines were generated; 67, 71, 76, 95, and 30. This line has a copy number of 22 and is one of the moderate-expressing lines. (J:137813)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
