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A mouse bacterial artificial chromosome (BAC) RP24-384G12 containing the entire Abcb1a gene was modified by insertion of the EGFP/Rpl10a fusion gene (containing a stop codon and polyA stop) between the transcriptional start site and the promoter. No other genes are expressed from the BAC. Part of the Rundc3b gene is present, but it does not appear to be expressed since it is a partial gene. This has been confirmed with RNAseq data from brain tissue from these mice. (J:242483)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
