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EN
A loxP site flanked neomycin resistance gene cassette was inserted upstream of exon 1. A 15 amino-acid Avi tag was inserted in-frame with the gene so that the resulting translated peptide would have an N-terminal biotinylation tag. The insertion of the neo cassette is intended to interfere with transcription of the gene and was shown by RT-qPCR to indeed reduce expression to around 27% of wild-type. (J:240473)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
