Sik2^tm1.1Mfor

An frt site flanked hygromycin resistance gene cassette was inserted in intron 4. Exon 5 was flanked by loxP sites. Exon 5 codes for part of the active catalytic domain including the Thr175 phosphorylation site within the activation loop. The hygro cassette was removed through subsequent FLP-mediated recombination, leaving a conditional-ready allele with a floxed exon 5. (J:242343)