A targeting vector was designed to insert a loxP site upstream of exon 1 and a frt-flanked neomycin resistance (neo) cassette, followed by a second loxP site, downstream of exon 2. Flp-mediated recombination deleted the neo cassette. (J:285796)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count