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A loxP site was introduced 5' of exon 1 and a FRT-flanked PGK-neomycin cassette and loxP site were placed in intron 1 via homologous recombination. The neo cassette and exon 1 were deleted by transiently transfection of an expression vector of Cre recombinase in the ES cells. (J:281818)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
