Syt14^em1(IMPC)J

This allele from project Syt14-8616J-6466M was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences GCTCTCCTTGGCAACCACGG, TAAGGTACGAGAAGCTACAA, CTTATTGGATGAGAGGAGAG and TTATGAATTCTACACAGCAT, which resulted in a 544 bp deletion beginning at Chromosome 1 negative strand position 192,933,556 bp, GAGAGTGGAAAGCTAAGGAA, and ending after CAGTGTCTCATCCCTTGTAG at 192,933,013 bp (GRCm38/mm10). This mutation deletes exon 5 and 272 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 148 and early truncation 11 amino acids later. (J:188991)