The targeting vector consists of a diphtheria toxin A-negative selection cassette (DTA) followed by exons 3 to 6 flanked by loxP sites and a neomycin-positive selection cassette (NeoR) flanked by frt sites downstream of exon 6 but before the loxP site. Cre-mediated recombination removed exons 3-6 and the NeoR cassette. (J:241919)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
Insertion, Intragenic deletion
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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