CRISPR/Cas9 targeting exon 12 through 16 created a 12 kb deletion of the targeted exons that encodes the SAM domain. mRNA expression analysis confirmed normal expression levels of the modified transcript. (J:231477)
Basic Information
(129S6/SvEvTac x C57BL/6NCrl)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count