The enhanced green fluorescent protein (EGFP) is fused to the 3' end of the gene, which carries a S193A (TCC->GCC) mutation, followed by an FRT-flanked PGK-neomycin selection cassette. Flp-mediated recombination removed the FRT-flanked neo cassette. GFP expression has been observed in cerebellar granule neurons, deep cerebellar nuclei, hindbrain nuclei, spinal cord interneurons, secretory intestinal cells, Merkel cells, and inner ear hair cells. (J:248783)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6N-Atm1Brd
Targeted
Insertion, Nucleotide substitutions
--
1
1
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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