CRISPR/Cas9 technology introduced a 135 bp deletion in the single coding exon. Western blot analysis confirmed the absence of protein expression in limb and tongue at E16.5 and P0. (J:241565)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count