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The L1L2_Bact_P cassette was inserted at position 25287449 of Chromosome 7. The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site inserted into intron 8. A third loxP site is inserted in intron 11. Cre-mediated recombination removed the loxP-flanked portion of the construct, leaving a 5'FRT site, the En2 splice acceptor-IRES-lacZ-pA cassette, and a 3' loxP site. (J:240674)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
