LoxP sites were introduced into intron 1 and exon 2. Flp-mediated recombination removed the 5' FRT-flanked selection cassette and left exon 2 floxed. (J:241561)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count