Plasmids encoding a signal guide RNA designed to introduce a cre/ERT2 knock-in mutation into 3' UTR near the stop codon of the Mgam gene and the cas9 nuclease were introduced into the cytoplasm of C57BL/6N-derived JM8.N4 ES cells. (J:159099)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count