Cul3^tm2Suc

A mutation in the C terminus of intron 8, c.1207-6T>G, was knocked into the locus along with a floxed neo cassette after exon 9 that was subsequently removed via cre-mediated recombination. This is one of the reported Pseudohypoaldosteronism type II-causing mutations in this gene in humans. (J:226618)