A loxP site is inserted in intron 2 and an FRT-loxP-neomycin-FRT-loxP cassette was introduced to intron 3. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exon 3 floxed. (J:241281)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count